Leaders | Players | Teams | Award Races
| Pos | Player | Team | GP | G | A | Pts | +/- | PIM | PP | SH | GW | GT | Hits | Shots | % |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LW | * Rick Nash | | 81 | 30 | 30 | 60 | 7 | 81 | 4 | 0 | 2 | 1 | 44 | 186 | 16.1 |
| LW | * Brenden Morrow | | 79 | 24 | 35 | 59 | -8 | 91 | 9 | 1 | 3 | 0 | 211 | 196 | 12.2 |
| LW | * Ruslan Khasanshin | | 83 | 23 | 33 | 56 | -8 | 86 | 3 | 1 | 1 | 1 | 160 | 180 | 12.8 |
| LW | Jamie Benn | | 76 | 21 | 30 | 51 | 12 | 41 | 5 | 2 | 5 | 0 | 152 | 186 | 11.3 |
| C | * Alexei Ivanov | | 82 | 18 | 31 | 49 | -7 | 94 | 6 | 0 | 3 | 0 | 117 | 182 | 9.9 |
| D | * Carlo Colaiacovo | | 79 | 10 | 38 | 48 | 7 | 115 | 1 | 1 | 2 | 0 | 189 | 158 | 6.3 |
| RW | James Neal | | 79 | 18 | 27 | 45 | 0 | 77 | 5 | 0 | 2 | 0 | 107 | 152 | 11.8 |
| RW | Adam Burish | | 77 | 19 | 25 | 44 | 5 | 383 | 0 | 1 | 4 | 2 | 234 | 129 | 14.7 |
| C | * T.J. Hensick | | 80 | 13 | 28 | 41 | 8 | 59 | 0 | 2 | 3 | 0 | 59 | 115 | 11.3 |
| D | Nicklas Grossman | | 82 | 9 | 24 | 33 | 6 | 88 | 2 | 1 | 2 | 0 | 106 | 91 | 9.9 |
| C | * Dmitri Kazionov | | 82 | 15 | 14 | 29 | 5 | 44 | 2 | 0 | 3 | 0 | 29 | 105 | 14.3 |
| D | * Jonathan Blum | | 80 | 11 | 18 | 29 | -1 | 56 | 1 | 1 | 1 | 0 | 76 | 138 | 8.0 |
| D | Calvin de Haan | | 79 | 5 | 20 | 25 | 4 | 50 | 1 | 2 | 0 | 0 | 53 | 132 | 3.8 |
| D | Aaron Ness | | 79 | 6 | 18 | 24 | -7 | 91 | 0 | 0 | 0 | 0 | 111 | 137 | 4.4 |
| D | Matt Lashoff | | 83 | 2 | 17 | 19 | 1 | 89 | 0 | 0 | 0 | 0 | 275 | 115 | 1.7 |
| D | * Chad Billins | | 71 | 0 | 5 | 5 | -2 | 11 | 0 | 0 | 0 | 0 | 6 | 13 | 0.0 |
| LW | * Brandon Bollig | | 41 | 1 | 3 | 4 | -8 | 67 | 0 | 0 | 0 | 0 | 38 | 26 | 3.8 |
| C | * Geoff Paukovich | | 14 | 1 | 3 | 4 | -7 | 64 | 0 | 0 | 0 | 0 | 14 | 14 | 7.1 |
| RW | * Michal Pesek | | 13 | 0 | 4 | 4 | -1 | 9 | 0 | 0 | 0 | 0 | 10 | 14 | 0.0 |
| LW | Matt Martin | | 38 | 1 | 2 | 3 | 0 | 30 | 1 | 0 | 0 | 0 | 7 | 10 | 10.0 |
| D | * Ian White | | 1 | 1 | 1 | 2 | 2 | 6 | 0 | 0 | 0 | 0 | 1 | 4 | 25.0 |
| D | Brian Strait | | 40 | 0 | 1 | 1 | -3 | 18 | 0 | 0 | 0 | 0 | 21 | 14 | 0.0 |
| RW | * Eric Fehr | | 37 | 0 | 1 | 1 | -2 | 14 | 0 | 0 | 0 | 0 | 6 | 14 | 0.0 |
| C | * Joonas Nattinen | | 4 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 5 | 0.0 |
| D | * Mikko Jokela | | 6 | 0 | 1 | 1 | -3 | 8 | 0 | 0 | 0 | 0 | 6 | 8 | 0.0 |
